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Year : 2014  |  Volume : 34  |  Issue : 1  |  Page : 27-35

Prevalence of cutaneous manifestations in chronic renal failure patients on regular hemodialysis: a hospital-based study

1 Dermatology and Venereology Department, Faculty of Medicine, Benha University, Benha, Ethiopia
2 Department of Dermatology and Venereology, Misr University for Science and Technology, 6th October city, Ethiopia
3 El Mahalla Elkobra town, Ethiopia

Correspondence Address:
Neveen E Sorour
MD, Dermatology and Venereology Department, Faculty of Medicine, Benha University, Benha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1110-6530.137278

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Background Chronic renal failure (CRF) presents with an array of cutaneous manifestations. Newer changes are being described since the advent of hemodialysis (HD), which prolongs life expectancy, providing time for these changes to manifest. Objective The aim of this study was to estimate the prevalence and pattern of cutaneous manifestations among patients with CRF on regular HD. Patients and methods This case-series study included 100 patients with CRF on regular HD. They were subjected to a full assessment of history, and general and dermatological examinations of the skin, hair, nails, and oral mucosa. Results All patients included in this study had at least one cutaneous manifestation attributed to CRF. The most prevalent finding was xerosis (72%), followed by pruritus (52%) and hyperpigmentation (44%), whereas purpura (2%) and bullous dermatosis (1%) were the least detected. Oral changes included xerostomia (46%), macroglossia with teeth markings (43%), fissured tongue (17%), ulcerative stomatitis (11%), and angular cheilitis (6%). The most common nail changes were absent lunula (61%), half and half nail (41%), and koilonychia (29%). Hair changes included sparse scalp hair (48%), sparse body hair (41%), and brittle and lusterless hair (39%). Hypertension and diabetes mellitus were the most common causes of CRF (53 and 18%, respectively). Conclusion Every CRF patient on HD had at least one cutaneous manifestation, which may appear before or after HD. The most common cutaneous manifestations were xerosis, pruritus, hyperpigmentation, xerostomia, macroglossia, absent lunula, half and half nail, sparse scalp hair, and sparse body hair.

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