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Year : 2016  |  Volume : 36  |  Issue : 1  |  Page : 11-17

Quality of life of Egyptian patients with psoriasis: a hospitalbased cross-sectional survey

1 Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Alexandria, Egypt
2 Department of Community Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt

Correspondence Address:
Amira A Eid
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Elazarita 21521, Alexandria
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1110-6530.194155

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Background Quality-of-life (QOL) impairment caused by psoriasis is well documented and is comparable to serious diseases. Several patient-related and disease-related factors can influence the final impact of psoriasis on the QOL. Aims The aims of this study were to assess the QOL of Egyptian patients with psoriasis and to explore factors affecting the QOL in those patients. Patients and methods A total of 274 patients (179 male and 95 female) with chronic plaque-type psoriasis were enrolled in the study. Disease severity was assessed using the Psoriasis Area Severity Index (PASI) and patients were asked to answer the Dermatology Life Quality Index (DLQI). DLQI scores and subscores were calculated, and the impact of different patient and disease characteristics on the DLQI was evaluated. Results The DLQI in patients ranged from 1.0 to 26.0. In 0.7% of the patients, psoriasis exerted no effect on the DLQI, small effect was reported in 10.6% of patients, moderate effect in 28.1% of patients, very large effect in 54% of the patients, and extremely large effect in 6.6% of the patients. A significant direct correlation between the PASI and the DLQI was detected (P<0.001). Both age (r=−0.19, P=0.002) and age at disease onset (r=−0.17, P=0.004) were negatively correlated with the DLQI. Multivariate linear regression analysis revealed the PASI to be an important predictor for QOL impairment in the studied patients. Conclusion The PASI may be a pivotal factor in determining the final impact of psoriasis on the QOL of Egyptian patients.

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